Pan-immune-inflammation value in FMF patients

Objective: Familial Mediterranean fever (FMF) is the most common disease that leads to secondary amyloidosis related persistent subclinical inflammation in Turkish patients. Pan-immune-inflammation value (PIIV), a recently-developed index validated predict prognoses of several malignancies. We investigated PIIV FMF Material and Methods: included 100 patients with regular follow-ups, defined as at least two visits yearly. Demographic characteristics, prominent attack features, treatment choices were noted. also calculated other inflammation-related laboratory results attack-free periods. In comparative analysis quantitative data, Student's t-test (for normal distribution) Mann-Whitney U test non-normally used. P <0.05 was accepted statistically significant value. Results: A total study. Forty-two male, whereas fifty-eight female. The between 18 69 years old, mean age study group 39.65 ± 13.83 years. MEFV mutation analyses eighty-six present medical record system. Exon 10 mutations detected 67 (77.9%) patients, non-exon (exon 2 3) 8 (9.3%) Homozygous 19 (22.1%). Although acute phase reactants, including erythrocyte sedimentation rate (ESR), c-reactive protein (CRP), serum amyloid (SAA), significantly higher homozygous exon mutations, there no statistical difference groups. Conclusion: similar recent literature northern part country. need for biological agents male gender compared